suppressor gene

Analytical and technical consideration of P53 tumor suppressor gene mutation

P53肿瘤抑制基因突变分析的技术方法探讨

The methylation of promoter region CpG islands is one of main ways for inactivating tumor suppressor gene, DNA repair gene and pro-apoptotic gene.

启动子区CpG岛高甲基化（hypermethylation）是抑瘤基因、DNA修复基因、促凋亡基因失活的主要方式之一。

Caused by the methylation of gene silencing the tumor, available through DNA methyltransferase non-competitive or competitive inhibitors methylation occurs, activating the silence of the tumor suppressor gene, so as to achieve the aim of the treatment of tumors.

由甲基化引起基因沉默而出现的肿瘤，可通过DNA甲基转移酶非竞争性或竞争性抑制剂抑制甲基化的发生，活化沉默的抑癌基因，从而达到治疗肿瘤的目的。

A study of correlation between of occurrence of Wilms' tumor with p53 tumor suppressor gene mutation

小儿肾母细胞瘤的发生与p53抑癌基因突变关系的研究

Expression of Tumor Suppressor Gene PTEN in Oral Squamous Cell Cancer Using Tissue Microarray Techniques

应用自制组织芯片研究抑癌基因PTEN在口腔鳞癌中的表达

PTEN ( also designated MMAC 1 ) gene is a new tumor suppressor gene a lipid phosphatase.

PTEN基因亦称MMAC1基因,是一种新发现的肿瘤抑制基因.

Objective To investigate the new progresses in tumor suppressor gene PTEN and esophageal carcinoma ( EC ).

目的了解抑癌基因PTEN在食管癌 ( EC ) 中的最新研究进展.

P53 is one of the most widely and deeply studied oncogene, a tumor cells suppressor gene that exists in almost all human tumors.

P53抑癌基因是细胞抑癌基因中研究最广泛和深入的基因之一，p53基因的异常几乎存在于人类所有的肿瘤。

Objective To investigate expression and significance of tumor suppressor gene PTEN in esophageal carcinoma.

目的探讨抑癌基因PTEN在食管癌中的表达及临床意义.

Objective: To study P53 suppressor gene mutation of pancreatic neoplasm in the Inner Mongolia Autonomous Region.

目的：了解内蒙古地区胰腺癌患者P53抑癌基因的突变情况。

The study of molecular pathogenesis in medulloblastoma: Single-strand conformation polymorphism analysis of PTEN tumor suppressor gene

髓母细胞瘤分子病理学研究：PTEN抑癌基因单链构型多态性分析

MiRNAs is a new kind of small molecular RNA which play the role of oncogene or tumor suppressor gene.

miRNAs是一类新发现的在肿瘤中发挥癌基因或抑癌基因样作用的小分子RNA。

Expression of the tumor suppressor gene P~ ( 16) in arsenic keratosis by hybridization in situ

原位杂交检测砷角化病表皮P~（16）基因的表达

As a complex process, infiltration and metastasis of malignant tumor is associated with motility, motility factor with its receptor, signal transduction, hereditary defect, tumor metastasis-related gene and tumor suppressor gene.

肿瘤的浸润和转移是一个复杂的过程，与肿瘤细胞的能动性、能动性因子及其受体、转移的信号转导、肿瘤细胞的遗传性缺陷、肿瘤转移相关基因及肿瘤抑制基因等诸多因素相关。

Objective To study the potential value of RECK, a transformation suppressor gene, as a prognostic molecular marker for glioma.

目的探讨肿瘤抑制基因RECK作为胶质瘤预后指标的潜在价值，及相关金属蛋白酶MMP-9、MMP-2在胶质瘤中的变化与RECK的相互关系。

Detection of p53 Tumor Suppressor Gene Mutation in Nine Kinds of Malignant Lymphoma Cell Lines Using PCR-SSCP Technique

银染PCR-SSCP方法检测人9种恶性淋巴瘤细胞系p53抑癌基因的突变

Objective To investigate the relationship between methylation of tumor suppressor gene and gastric cancer.

目的探讨肿瘤抑制基因甲基化与胃癌的关系.

If the suppressor gene mutation may lead to disorders and cancerous cell growth.

如果抑癌基因发生突变,也可导致细胞生长失调而发生癌变.

Neurofibromatosis type 1 ( NF1) is a common, autosomal-dominant disorder caused by mutations in the NF1 tumor suppressor gene.

神经纤维瘤病（NF1）是常见的常染色体显性遗传性疾病，国外报道，其发病率高达1：3000。这种疾病是由于NF1基因的突变而发生的。

Objective: Study the expression of tumor suppressor gene, DNA repair gene and telomerase component in acute leukemia, discuss their effects on the occurrence and development of leukemia and their clinical meanings.

目的：研究抑癌基因、DNA修复基因及端粒酶在白血病细胞中的表达，探讨其对白血病发生、发展的作用和临床意义。

They also raise the possibility that this important tumor-suppressor gene might play a role in miscarriages.

同样,这个重要的抑癌基因可能在流产中产生了重要的作用,它增加了流产发生的可能性.

E-cadherin can suppress tumor cell invasion and metastasis, and is considered as an invasion/ metastasis suppressor gene.

E-cadherin能抑制肿瘤细胞的浸润和转移，被公认为是浸润、转移抑制基因。

P 53 gene is found in human tumors so far the most relevant tumor suppressor gene.

P53基因是迄今发现与人类肿瘤相关性最高的抑癌基因.

Conclusion: RECK gene is supposed to be a tumor suppressor gene which may act by inhibiting the activity of MMPs.

结论：RECK基因在前列腺癌中的表达量明显下降，而MMP-2、MMP-9的表达量明显升高，RECK基因可能通过抑制MMP-2、MMP-9的表达起到抑癌基因的作用。

Three regions had the signature of a tumour suppressor gene, but many looked like fragile sites.

3个区域具有肿瘤抑制基因的信号, 但多数看起来象脆性位点.

P53 tumor suppressor gene mutation and protein accumulation in multifocal esophageal precancerous lesions among high risk population in Henan

食管癌高发区人群多灶性食管癌前病变的P53肿瘤抑制基因变化研究

Recent evidence suggests that Tob could be a tumor suppressor gene in lung cancer.

最近的研究表明:在肺癌的发病机制中Tob可能为抑癌基因.

Epigenetic Regulation of Tumor Suppressor Gene PTEN and Its Anticancer Mechanisms

肿瘤抑制基因PTEN的表观遗传调控及其抗肿瘤机制研究

Objective To study the relationship between tumor suppressor gene PTEN , P 16, P 15 and primary cervical carcinomas.

目的探讨肿瘤抑制基因PTEN, P16, P15与原发性宫颈癌之间的关系.

Study on the expression of tumor suppressor gene p53 by RNAi technology

RNA干涉技术用于p53基因表达的研究